From the list of serology tests under FDA Emergency Use Authorization (EUA) validation results, it appears that there are two methods used in diagnostic tests for COVID-19 antibodies: ELISA and Simple or Rapid tests. Both diagnostics tests can be used in preliminary or emergency medical screening.
The need for these timely and accurate COVID-19 laboratory testing solutions is to help mitigate the spread of corona virus, guide decision making and identify individuals in a particular population with strong immune response to SARS-CoV-2. These coronavirus resistant patients may donate a part of their blood or convalescent plasma to aid in the development of treatment for the vulnerable population.
A Physician may recommend either a rapid or ELISA IgG test when an individual starts developing signs or symptoms of the coronavirus. In this article we will determine the difference between the two screening methods for the detection of COVID-19 antibodies.
ELISA (enzyme-linked immunosorbent assay), also called EIA is a type of screening technology that is mostly used to detect and measure antibodies in a blood sample. This testing method can be used on certain infectious conditions such as that of COVID-19. This type of test is usually done by a scientist or health professional and is designed to detect the Immunoglobulin G (IgG) antibody.
The Centers for Disease Control and Prevention (CDC) uses their SARS-CoV-2 spike ELISA tests to detect the presence of IgG and IgM antibodies in blood samples. These samples are obtained from individuals who have tested positive and negative for coronavirus confirmed by a nucleic acid amplification test, or NAAT. This shows that an ELISA test can be used to diagnose COVID-19.
The ELISA screening is an antigen-based diagnostic test that can be used to detect antibodies. This method of screening or testing is simple and straightforward. It involves the collection of blood samples from an infected individual and sending it to the lab for analysis. The sample is added to a petri dish containing the COVID-19 antigen. If the blood sample contains IgG antibodies, they will bind with the antigens in the dish.
While the antigen and antibodies start to react, the technician will add an enzyme to the mixture and observe the reaction between antigen and blood sample. The content on the dish will chance color to show the presence of SARS-CoV-2 antibodies in the specimen. The amount of change helps in determining the amount of IgG and IgM antibodies in the blood sample.
This test is usually used to identify positive and negative samples in preparation of measuring the “sensitivity” and “specificity” estimates of a COVID-19 antibody test kit. There is a possibility of getting false positive and false negative results. The positive and negative predictive values (PPV and NPV) of these tests varies depending on the following factors:
- Testing environment conditions
- The quality of sample collected
- Time from onset of symptoms
- Concentration of coronavirus in the specimen
For you to use this testing method, you will need sophisticated equipment, constant supply of electricity and skilled lab technicians. This equipment must be regularly maintained to get reliable results.
- They can be used to determine the number of antibodies in a blood sample
- These tests are highly sensitive and specific
- They are suitable for testing large numbers of samples per day
Simple or rapid test are also known as antibody or serology tests. These tests are often categorized as point-of-care immunodiagnostic tests because they can be outside of laboratory settings. They are Rapid tests because the results are available in a couple of minutes, usually within ten minutes. Rapid test is the most common diagnostic test for COVID-19 antibodies.
The diagnosis of COVID-19 infections using rapid test is usually done during the recovery phase since most patients develop coronavirus antibodies only in the second week after the onset of symptoms. Furthermore, there is a high chance of cross reactivity when using this antibody detection method.
The test makes use of a coronavirus antibody testing kit to facilitate the detection of antibodies against SARS-CoV-2 in a whole blood sample. Simple or Rapid screening make use of test cassettes similar to those used in pregnancy tests. It also requires a blood sample which is usually drawn from the fingertip of a patient.
The technology used in these rapid COVID-19 test kits, lateral flow, makes it easy and quick for health professionals to perform medical diagnostic tests for preliminary or emergency screening. Most rapid tests are designed to detect both immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies.
Rapid tests will have less false positive results when used in a population with a high prevalence of COVID-19 as opposed to the general population. These tests are less accurate in cases from recent Corona virus infection. Generally, the accuracy of the results will depend on the sensitivity and specificity of the COVID-19 antibody test kit. Rapid tests that are performed by experienced staff give more accurate results.
The rapid antibody test kits for Coronavirus are designed for use in hospital laboratories or near the point-of-care. Currently, there are two types of COVID-19 rapid tests: direct SARS-CoV-2 antigen and indirect antibody detection.
- More economical than ELISAs in low throughput or smaller laboratories.
- Useful where there are limited resources
- Provides same-day results
- Requires limited test administrator training
- They do not require well-equipped laboratory facilities
For emergency response, the Rapid test method is the most appropriate. Since you will need reliable coronavirus antibody test kits, it is best that you look for the ones that comes with a CE marking, a confirmation that the device conforms to European health and safety standards. If you are in the US, then choosing kits that are authorized by the Food and Drug Administration (FDA) is a must.
Lucky for you, Rapid Connect Medical distributes FDA EUA authorized Coronavirus (SARS-CoV-2) IgM/IgG rapid test kits that also come with CE Declaration. Feel free to contact Rapid Connect Medical whenever you need to place your bulk order.
Just in case you are wondering where you can place your COVID-19 antibody test kit order; Rapid Connect Medical has in place a rapid-ship response team ready to handle your test kit orders. Contact us today if you have any questions.
Rapid Connect Medical is now offering a U.S.A. manufactured, FDA EUA Authorized Covid-19 antibody rapid test kit. This antibody test kit is on sale for 50% off it’s normal price for the month of August. These 25 test kit packs is to be administered by a licensed medical professional.
A range of affordable mass screening point-of-care tests are available on order from different authorized distributors such as Rapid Connect Medical. This company allows companies and investors to make bulk test kit orders through its rapid-ship response team. If you would like to get more information on the testing capability of their covid-19 antibody test kits, feel free to contact Rapid Connect Medical and place your order today.
The sampling done with the rapid COVID-19 antibody test kit cassette using lateral flow from Rapid Connect Medical will give you the IgG and IgM detectable diagnostics results from between two and ten minutes. It can be used for reference in combination with the results from an RT-PCR (reverse transcriptase-polymerase chain reaction) test. A single finger prick to draw blood can be used with our kit that detects antibodies. This positive or negative result can be detected as soon as 3 days after exposure to COVID-19 (sometimes before the onset of symptoms occur).
Knowing if you have active igM antibodies even in the first week of infection can help get the best treatment for an infected person. If you do test positive, potentially exposed, or have traveled to a region with high infection rates, you should seek care from your doctor for treatment and continue to test for IgG antibodies daily until you are cleared to leave quarantine. The sensitivity, specificity, and accuracy or our antibody test kit is very high. This testing method for the public gives real time results and helps to identify initial infection before the severe flu like symptoms begin. This kit is intended to be administered by a health care professionals and providers.
The kits used for diagnostic tests for COVID-19 antibodies are usually designed for research use or qualitative detection of coronavirus, and not home use. Also, they can only be used to test the presence of IgG and IgM antibodies against SARS-CoV-2. Since they are aiding tools to RT-PCR or CT scanning, a clinical diagnosis of COVID-19 should be done by a healthcare professional or physician.
An antibody detection test cassette contains antigens from SARS-CoV-2 combined with gold nanoparticles. The device has two wells (one for specimen and one buffer) and a control region on the upper end. Two types of antibodies are of great importance in diagnostic tests for COVID-19 antibodies: Immunoglobulin M (IgM) and Immunoglobulin G (IgG).
The importance of the gold nanoparticles in the detection test cassette is to create a colored line in the control region. Antigens targeting a specific antibody are located in their respective regions on the nitrocellulose membrane of the test cassette. The IgG and IgM regions are coated with anti-human antibodies for each.
The rapid COVID-19 antibody test kits you will find on the market are designed to detect SARS-CoV-2-specific antibodies. The ones distributed by Rapid Connect Medical are FDA research approved and evaluated and validated by a comprehensive clinical study. This antigen test kit was developed in response to the COVID-19 global pandemic and offers a power tool for health care providers. The immune response produced by a Coronavirus viral infection is what this test measures. The CDC testing standards for laboratories were strictly followed during the clinical trials for our antibody test kit.
This is a serology elisa based test for SARS-CoV-2 antibodies in serum or plasma components of blood. Information on the collection data, total sample size, and validation of lab samples can be found here for review. Interpretations of test results should be confirmed with a lab and a a medical professional should diagnose your infection status not only on the sole basis of your rapid test kit results. This rapidtest should be performed by a licensed medical professional and your infection status determination may require additional tests. With the presence for IgG antibodies people can have immunity for some time. While viruses such as influenza have been a problem in the past, Covid-19 is a serious problem we aim to help eliminate.
Rapid Connect Medical distributes large orders of Coronavirus (SARS-CoV-2) IgM/IgG rapid test kits to global professional sports league and arenas. Rapid Connect Medical is the leading provider of Covid-19 Antibody test kits in small quantities, 25 test kit packs, as well as bulk orders for large countries, companies, and organizations. If your institute or corporation is in the need of antibody test kits, feel free to email our sales team. The company covers the USA, Canada, South America, and European territories. Therefore, if you are from these areas, Rapid Connect Medical will be able to assist you with availability, pricing, and ordering. Our test kit is considered to be the best product on the market for rapid Covid-19 antibody testing.
Our test kits are FDA EUA (Emergency Use Authorization) Authorized, have the CE Declaration for authorized European Union distribution, and have an authorization for use by the HHS for Pharmacies and Pharmacists. Federal guidance has been issues for Rapid Connect Medical’s COVID-19 Antibody test kit that is 98.20% accurate with results in 2 to 10 minutes. Don’t take a risk using inferior test kits, our Antibody Test kits are tested in a biotechnology laboratory!
The development of the technology for this screening standard with confirmed scientific accuracy is unique to Rapid Connect Medical‘s Antibody Test Kit. If you are interested in order a large quantity for commercial, biomedical, biological, science, or pharmaceutical applications and have questions, feel free to book a call with our sales team. In response to the global demand, our manufacturers have the capacity to support your required production needs. Covid-19 testing is also covered by many insurance plans. For our update on insurance coverage from our website, that can be accessed here.
Certification and Authorization – COVID-19 antibody test kits from Rapid Connect Medical are safe for use under the Emergency Use Authorization (EUA) of the FDA (Food and Drug Administration). They also are authorized by The U.S. Department of Health and Human Services (HHS) for Pharmacy or Pharmacist use. The antibody test kits come with a CE Declaration, meaning that they are clear for use in countries that fall under the European Union.
Storage and Quality – the Coronavirus antibody testing kits from Rapid Connect Medical have a shelf life of 24 months from the date of manufacture.
Ease of Use – the COVID-19 antibody test kits from Rapid Connect Medical are easy to use and you can get your results in two to ten minutes. The antibody test kits are designed for medical professional use and not as an over-the-counter product for home use.
Technology – the rapid serologic COVID-19 antibody test kits from Rapid Connect Medical use lateral flow technology.
We offer fast shipping methods for our antibody test kits at an affordable rate. You can order test kits online at https://rapidconnectmedical.com/
Be sure to follow us on Facebook, LinkedIn, YouTube, and Twitter for updates, news, and new product announcements. We will also be having press events in the near future so keep an eye out for more news about Rapid Connect Medical!