Everyone is looking for reliable information about the accuracy of COVID-19 antibody tests, a testing approach that is different from the norm. The need to use this testing technique has been influenced by the possibility of someone getting infected by the coronavirus and fail to show any of the symptoms associated with the disease.
When it comes to COVID-19 antibody or serological tests, there are two main types of testing methods you can use: enzyme-linked immunosorbent assay (ELISA) and lateral-flow immunoassay (LFIA). The ELISA test is laboratory-based, while that of LFIA is point-of-care or cassette based. The design and technology of LFIA rapid tests borrow a lot from the home pregnancy tests (HPTs).
All diagnostic tests done for coronavirus aim to provide 100% accurate results, and this is not different with that for COVID-19 antibodies. The antibodies of interest in a COVID-19 antibody test are the acute-phase immunoglobulin M (IgM) and late-phase immunoglobulin G (IgG).
In this section of the article we’ll go through some of the draw backs that you are likely to come across while using this method to determine the spread of COVID-19 infection in a target population.
- False Negative
According to the U.S. Centers for Disease Control and Prevention (CDC), some people develop antibodies to SARS-CoV-2 within the first week of symptom onset, while others can take longer. This shows that taking the COVID-19 antibody tests too soon can produce false negative result. The worst thing about having these kinds of results is that one can continue spreading the virus not knowing that they positive.
The rise in false negative and false positive results in the use of rapid test kits has made the U.S. Food and Drug Administration (FDA) and other agencies take a closer and keener look at these COVID-19 antibody tests. With the strict measures in place, we are bound to see an improvement of the test designs making them more reliable, showing the true scale of how the coronavirus disease is spreading.
- False Positive and Cross Reactivity
Another issue that is common with COVID-19 antibody tests high rates of false positive results. These results can mean either the coronavirus antibody testing kit is highly sensitive or there is a case of cross reactivity. In terms of cross reactivity, instead of detecting SARS-CoV-2 antibodies the test might detect antibodies to ARS-CoV or MERS-CoV- if present in the blood sample.
- Results Are Only for Research
We all want to go back to a sense of normalcy, but this won’t be possible for now until diagnostic tests for COVID-19 are improved or when a vaccine is ready. The results from COVID-19 antibody tests are meant for population prevalence studies. The U.S. Centers for Disease Control and Prevention (CDC) advises against using the findings from these tests to return employees back to their workplaces.
- For Hospital and Laboratory Use
Unfortunately, COVID-19 antibody tests are designed for hospital and laboratory use. As much as they are point of care testing devices, the design of most COVID-19 antibody test kits is meant for use by skilled medical personnel or well-trained operator.
Generally, COVID-19 antibody tests are considered as sources of knowledge and insight on the spread of the novel coronavirus. The results are useful in guiding decision making and understanding the virus and disease. Here are some of the advantages of using this method of testing for antibodies to SARS-CoV-2:
- No Delay of Results
The reason why COVID-19 antibody tests are more popular is due to the fact that they can be used to identify positive cases in minutes. Results from a rapid COVID-19 antibody test kit are usually ready for reading and interpretation within ten minutes.
- History of Viral Infection
COVID-19 antibody tests with high sensitivity (true positives) and high specificity (true negatives) help a lot in correctly identifying people with and without antibodies to coronavirus. The presence of antibodies in the blood sample clearly shows that the novel coronavirus infections is ongoing or one had previously contracted it.
What we cannot tell about a COVID-19 infection is when someone may have contracted the SARS-CoV-2 disease. The best we can do is to rely on symptoms and diagnostic tests that are designed to reveal our status and level of infection, either mild or severe. With COVID-19 antibody tests, the presence of IgM and IgG can help in tracking dates – only if the lifespan of the protein is known.
- Source of Information on Immunity Levels
The presence of antibodies to COVID-19 is evidence enough that one can develop immunity against the disease. Knowing the immunity status of people in a particular study population will help determine the level of “herd” immunity.
Knowing the immunity status of an individual that has fully recovered COVID-19 automatically categorizes them as potential donors for convalescent plasma. This type of donations is highly appreciated by scientist who are working to develop treatment for patients that are severely ill from the coronavirus disease.
- Affordability and Ease of Use
COVID-19 antibody tests require the use of reliable coronavirus antibody test kits. These kits are affordable and come with a design that is easy to use the results from the test window. As much as the operator needs some training on the use of a rapid test, there are no additional complex equipment needed to use this testing method.
From the pros and cons we have listed in this article it is fair to say that COVID-19 antibody tests have more advantages and that the listed disadvantages can be improved to produce accurate and reliable results. Since this testing method is not usually used as the sole strategy for diagnosing acute COVID-19 infections, you can use it together with Nucleic acid-based tests to get more accurate results.
Distributors such as Rapid Connect Medical make it sure that organizations and health care facilities get reliable coronavirus antibody test kits. Feel free to contact us and place your bulk order today.
Rapid Connect Medical is an exclusive distributor of the FDA EUA authorized rapid COVID-19 antibody test kit. If you are an organization or a healthcare professional looking for reliable coronavirus antibody test kits to identify individuals who may have developed an immune response to coronavirus, SARS-CoV-2, then you are safe with Rapid Connect Medical as your antibody test kit partner.
Rapid Connect Medical is now offering a U.S.A. manufactured, FDA EUA Authorized Covid-19 antibody rapid test kit. This antibody test kit is on sale for 50% off it’s normal price for the month of August. These 25 test kit packs is to be administered by a licensed medical professional.
A range of affordable mass screening point-of-care tests are available on order from different authorized distributors such as Rapid Connect Medical. This company allows companies and investors to make bulk test kit orders through its rapid-ship response team. If you would like to get more information on the testing capability of their covid-19 antibody test kits, feel free to contact Rapid Connect Medical and place your order today.
The sampling done with the rapid COVID-19 antibody test kit cassette using lateral flow from Rapid Connect Medical will give you the IgG and IgM detectable diagnostics results from between two and ten minutes. It can be used for reference in combination with the results from an RT-PCR (reverse transcriptase-polymerase chain reaction) test. A single finger prick to draw blood can be used with our kit that detects antibodies. This positive or negative result can be detected as soon as 3 days after exposure to COVID-19 (sometimes before the onset of symptoms occur).
Knowing if you have active igM antibodies even in the first week of infection can help get the best treatment for an infected person. If you do test positive, potentially exposed, or have traveled to a region with high infection rates, you should seek care from your doctor for treatment and continue to test for IgG antibodies daily until you are cleared to leave quarantine. The sensitivity, specificity, and accuracy or our antibody test kit is very high. This testing method for the public gives real time results and helps to identify initial infection before the severe flu like symptoms begin. This kit is intended to be administered by a health care professionals and providers.
The kits used for diagnostic tests for COVID-19 antibodies are usually designed for research use or qualitative detection of coronavirus, and not home use. Also, they can only be used to test the presence of IgG and IgM antibodies against SARS-CoV-2. Since they are aiding tools to RT-PCR or CT scanning, a clinical diagnosis of COVID-19 should be done by a healthcare professional or physician.
An antibody detection test cassette contains antigens from SARS-CoV-2 combined with gold nanoparticles. The device has two wells (one for specimen and one buffer) and a control region on the upper end. Two types of antibodies are of great importance in diagnostic tests for COVID-19 antibodies: Immunoglobulin M (IgM) and Immunoglobulin G (IgG).
The importance of the gold nanoparticles in the detection test cassette is to create a colored line in the control region. Antigens targeting a specific antibody are located in their respective regions on the nitrocellulose membrane of the test cassette. The IgG and IgM regions are coated with anti-human antibodies for each.
The rapid COVID-19 antibody test kits you will find on the market are designed to detect SARS-CoV-2-specific antibodies. The ones distributed by Rapid Connect Medical are FDA research approved and evaluated and validated by a comprehensive clinical study. This antigen test kit was developed in response to the COVID-19 global pandemic and offers a power tool for health care providers. The immune response produced by a Coronavirus viral infection is what this test measures. The CDC testing standards for laboratories were strictly followed during the clinical trials for our antibody test kit.
This is a serology elisa based test for SARS-CoV-2 antibodies in serum or plasma components of blood. Information on the collection data, total sample size, and validation of lab samples can be found here for review. Interpretations of test results should be confirmed with a lab and a a medical professional should diagnose your infection status not only on the sole basis of your rapid test kit results. This rapidtest should be performed by a licensed medical professional and your infection status determination may require additional tests.
Rapid Connect Medical distributes large orders of Coronavirus (SARS-CoV-2) IgM/IgG rapid test kits to global professional sports league and arenas. Rapid Connect Medical is the leading provider of Covid-19 Antibody test kits in small quantities, 25 test kit packs, as well as bulk orders for large countries, companies, and organizations. If your institute or corporation is in the need of antibody test kits, feel free to email our sales team. The company covers the USA, Canada, South America, and European territories. Therefore, if you are from these areas, Rapid Connect Medical will be able to assist you with availability, pricing, and ordering. Our test kit is considered to be the best product on the market for rapid Covid-19 antibody testing.
Our test kits are FDA EUA (Emergency Use Authorization) Authorized, have the CE Declaration for authorized European Union distribution, and have an authorization for use by the HHS for Pharmacies and Pharmacists. Federal guidance has been issues for Rapid Connect Medical’s COVID-19 Antibody test kit that is 98.23% accurate with results in 2 to 10 minutes. Don’t take a risk using inferior test kits, our Antibody Test kits are tested in a biotechnology laboratory!
The development of the technology for this screening standard with confirmed scientific accuracy is unique to Rapid Connect Medical‘s Antibody Test Kit. If you are interested in order a large quantity for commercial, biomedical, biological, science, or pharmaceutical applications and have questions, feel free to book a call with our sales team. In response to the global demand, our manufacturers have the capacity to support your required production needs. Covid-19 testing is also covered by many insurance plans.
Certification and Authorization – COVID-19 antibody test kits from Rapid Connect Medical are safe for use under the Emergency Use Authorization (EUA) of the FDA (Food and Drug Administration). They also are authorized by The U.S. Department of Health and Human Services (HHS) for Pharmacy or Pharmacist use. The antibody test kits come with a CE Declaration, meaning that they are clear for use in countries that fall under the European Union.
Storage and Quality – the Coronavirus antibody testing kits from Rapid Connect Medical have a shelf life of 24 months from the date of manufacture.
Ease of Use – the COVID-19 antibody test kits from Rapid Connect Medical are easy to use and you can get your results in two to ten minutes. The antibody test kits are designed for medical professional use and not as an over-the-counter product for home use.
Technology – the rapid serologic COVID-19 antibody test kits from Rapid Connect Medical use lateral flow technology.
We offer fast shipping methods for our antibody test kits at an affordable rate. You can order test kits online at https://rapidconnectmedical.com/